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Updated: Jul 14, 2026

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
Thrombin injection for acute hemorrhage following angiography
T Richards1, F J Mussai, J Phillips-Hughes
1Nuffield Department of Surgery, John Radcliffe Hospital, Headington, Oxford, OX3 9DY, UK. tobyrichards@btinternet.com
Ultrasound-guided thrombin injection effectively treated uncontrolled bleeding after femoral arteriography in two cases. This minimally invasive approach avoided the immediate need for surgical intervention in these vascular access complications.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Medical Ultrasound
Background:
- Femoral arterial puncture is a common access route for vascular interventions.
- Uncontrolled bleeding is a rare but significant complication, often necessitating surgical repair.
Observation:
- Two cases of severe bleeding occurred post-femoral arteriography.
- Bleeding persisted despite initial conservative management.
Findings:
- Ultrasound-guided thrombin injection was successfully employed in both cases.
- The intervention achieved hemostasis, preventing immediate surgical intervention.
Implications:
- Ultrasound-guided thrombin injection offers a viable, less invasive alternative for managing post-procedural femoral bleeding.
- This technique may reduce the need for surgical exploration in specific vascular access complications.
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