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[Cytomegalovirus-induced protein-losing gastropathy: a case report]
C Pederiva1, A Ruscitto, I Brunetti
1Clinica Pediatrica, Ospedale San Paolo, Università di Milano.
Summary
Pediatric protein-losing gastropathy, or Menetrier's disease, is rare. This case highlights Cytomegalovirus (CMV) infection as a potential cause in children, suggesting a link between CMV and this uncommon condition.
Area of Science:
- Pediatric Gastroenterology
- Virology
- Pathology
Background:
- Protein-losing gastropathy, also known as Menetrier's disease, is an uncommon condition with uncertain causes.
- Pediatric cases are rare, typically presenting with a benign and transient course requiring supportive care.
Observation:
- A pediatric case presented with vomiting, weight loss, abdominal pain, and hypoalbuminemia.
- The patient exhibited hypertrophic gastropathy with significant protein loss.
Findings:
- Gastric mucosal biopsy confirmed morphological evidence of Cytomegalovirus (CMV) infection.
- This finding supports the hypothesis of CMV's role in the pathogenesis of pediatric Menetrier's disease.
Implications:
- Highlights the potential role of Cytomegalovirus in pediatric protein-losing gastropathy.
- Suggests diagnostic consideration of CMV in similar pediatric cases.
- Contributes to understanding the etiology of uncommon pediatric gastrointestinal disorders.
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