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Updated: Jul 14, 2026

Generation of Human Blood Vessel Organoids from Pluripotent Stem Cells
Published on: January 20, 2023
Building blood vessels--stem cell models in vascular biology
Lars Jakobsson1, Johan Kreuger, Lena Claesson-Welsh
1Department of Genetics and Pathology, Uppsala University, SE-751 85 Uppsala, Sweden.
Abstract:
Spheroids of differentiating embryonic stem cells, denoted embryoid bodies, constitute a high-quality model for vascular development, particularly well suited for loss-of-function analysis of genes required for early embryogenesis. This review examines vasculogenesis and angiogenesis in murine embryoid bodies and discusses the promise of stem cell-based models for the study of human vascular development.
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