Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Key issues in achieving an integrative perspective on stress.

Martin E Feder1

  • 1Department of Organismal Biology and Anatomy, The Committees on Evolutionary Biology, Genetics and Molecular Medicine, The College, The University of Chicago, 1027 E.57th Street, Chicago, IL 60637, USA. m-feder@uchicago.edu

Journal of Biosciences
|May 31, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evolution of heat-shock protein expression underlying adaptive responses to environmental stress.

Molecular ecology·2018
Same author

Engineering Candidate Genes in Studies of Adaptation: The Heat-Shock Protein Hsp70 in Drosophila melanogaster.

The American naturalist·2018
Same author

NATURAL VARIATION IN THE EXPRESSION OF THE HEAT-SHOCK PROTEIN HSP70 IN A POPULATION OF DROSOPHILA MELANOGASTER AND ITS CORRELATION WITH TOLERANCE OF ECOLOGICALLY RELEVANT THERMAL STRESS.

Evolution; international journal of organic evolution·2017
Same author

HERITABILITY OF EXPRESSION OF THE 70KD HEAT-SHOCK PROTEIN IN DROSOPHILA MELANOGASTER AND ITS RELEVANCE TO THE EVOLUTION OF THERMOTOLERANCE.

Evolution; international journal of organic evolution·2017
Same author

EXPERIMENTAL EVOLUTION OF HSP70 EXPRESSION AND THERMOTOLERANCE IN DROSOPHILA MELANOGASTER.

Evolution; international journal of organic evolution·2017
Same author

Anaerobic metabolism and behavior during predatory encounters between snakes (Thamnophis elegans) and salamanders (Plethodon jordani).

Oecologia·2017
Same journal

Hypercholesterolemia-induced impairment in sorafenib functionality is overcome by avasimibe co-treatment.

Journal of biosciences·2026
Same journal

Evolutionary trade-offs in plant immunity: prioritizing antiviral priming by herbivore-induced plant volatiles over defense against herbivores.

Journal of biosciences·2026
Same journal

Birds and bees do not express RAGE: comparative physiology and non-conventional model organisms hold the key to hyperglycemia tolerance.

Journal of biosciences·2026
Same journal

Distinct macrophage and microglia function in ischemic stroke.

Journal of biosciences·2026
Same journal

Dynamic attributes of the pedicel: Key drivers, structure and function in angiosperms.

Journal of biosciences·2026
Same journal

Cardiometabolomic signatures and gut microbiota dynamics in perinatally undernourished F<sub>1</sub> offspring: Decoding the metabolic footprint.

Journal of biosciences·2026
See all related articles

Understanding molecular mechanisms of stress resistance requires an integrative approach across all life forms and environments. Key unresolved questions concern the role of genetic variation and adaptive evolution in stress response.

Area of Science:

  • Ecology
  • Evolutionary Biology
  • Molecular Biology

Background:

  • An integrative perspective on molecular mechanisms of stress resistance necessitates understanding these processes across diverse contexts, from in vitro studies to societal and ecosystem levels.
  • Biological phenomena related to stress resistance operate at multiple organizational levels, from molecules to ecosystems, requiring contextual awareness.

Purpose of the Study:

  • To highlight three fundamental, unresolved issues crucial for developing an integrative perspective on stress resistance.
  • To stimulate interdisciplinary collaboration and meta-analysis for advancing the understanding of stress resistance mechanisms.

Main Methods:

  • This study is primarily theoretical, focusing on conceptual issues rather than empirical methods.
  • It emphasizes the need for careful attention to environmental context and diverse levels of biological organization.

Related Experiment Videos

Main Results:

  • Three fundamental issues remain unresolved: the significance of lower-level trait variation for stress resistance, the impact of environmental stress on genetic variation, and the extent to which adaptive evolution shapes organism distribution along stress gradients.
  • The study identifies these unresolved issues as critical barriers to an integrative understanding of stress resistance.

Conclusions:

  • Achieving an integrative perspective on stress resistance requires addressing fundamental questions about genetic variation, environmental stress impacts, and adaptive evolution.
  • Interdisciplinary collaboration and meta-analysis are proposed as essential strategies for resolving these complex issues and advancing the field.