[Clinical follow-up, histologic findings and therapeutic problems in a patient with bilateral ulcus rodens Mooren]

A severe, spontaneously acquired, bilateral, sight threatening Ulcus rodens Mooren of a 31 years old type I diabetic will be demonstrated in its clinical course. An improvement was achieved by a systemic immunomodulating therapy with Ciclosporin A that had to be tapered after 3 weeks due to severe side effects. The exclusive local therapy showed no effect at all. Later, the patient underwent a penetrating keratoplasty and extracapsular cataract extraction of both eyes under systemic Ciclosporin A therapy. The graft of the left eye failed due to a foudroyant bacterial infection whereas the keratoplasty of the right eye was successful up to this day despite of various complications.