Related Experiment Video
Updated: Jul 14, 2026

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis
Published on: October 13, 2016
Three soccer playing friends with simultaneous amyotrophic lateral sclerosis
Paul Wicks1, Jeban Ganesalingham, Christine Collin
1MRC Centre for Neurodegeneration Research, King's College London, Institute of Psychiatry, Department of Psychology, London, UK.
Three amateur soccer players developed amyotrophic lateral sclerosis (ALS) simultaneously. This case suggests that amateur soccer players may also face an increased risk of this neurodegenerative disease.
Area of Science:
- Neurology
- Epidemiology
- Motor Neuron Diseases
Background:
- Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative condition affecting motor neurons.
- The etiology of ALS is largely unknown, with limited understanding of potential environmental or occupational risk factors.
- Previous research indicated a possible increased incidence of ALS among professional soccer players in Italy.
Observation:
- A cluster of three amateur soccer players from the same region in southern England were diagnosed with ALS concurrently.
- These individuals were friends and participated in the same sport at an amateur level.
- The simultaneous diagnosis in a small, geographically linked group prompted further investigation.
Findings:
- The simultaneous occurrence of ALS in three amateur soccer players suggests a potential link between the sport and the disease.
- This observation expands upon previous findings in professional athletes, indicating a possible risk across different levels of play.
- Further epidemiological studies are warranted to investigate this potential association.
Implications:
- The findings suggest that participation in soccer, even at an amateur level, might be a risk factor for developing ALS.
- This highlights the need for broader research into environmental triggers and occupational hazards associated with ALS.
- Increased awareness and investigation are crucial for understanding and potentially mitigating risks for athletes in high-impact sports.
Related Concept Videos
Multiple Sclerosis l: Introduction
Cross-bridge Cycle
Satellite Stem Cells and Muscular Dystrophy
Parkinson Disease l: Introduction
Huntington Disease l: Introduction
Amyloid Fibrils
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining, normally used to...

