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Latanoprost-related transient incontinence.
Clinical & Experimental Ophthalmology
|June 2, 2007
Summary
Latanoprost, a common glaucoma treatment, rarely causes systemic side effects. This report details a rare case of temporary urge incontinence linked to latanoprost eye drops, confirmed by re-administration.
Area of Science:
- Ophthalmology
- Urology
Background:
- Latanoprost is a leading topical treatment for glaucoma.
- Common side effects are localized (e.g., hypertrichosis, iris pigmentation).
- Systemic adverse events are infrequent and generally mild.
Observation:
- A patient developed transient urge incontinence after starting latanoprost therapy.
- The incontinence resolved upon discontinuation and recurred upon re-initiation of latanoprost.
Findings:
- Challenge-rechallenge tests confirmed a causal link between latanoprost and urge incontinence.
- This suggests a potential, albeit rare, systemic effect of topical latanoprost.
Implications:
- Highlights the importance of considering systemic side effects even with topical medications.
- May prompt further investigation into the urological effects of prostaglandin analogs.
- Clinicians should be aware of this potential adverse event in glaucoma patients.
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