Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
Modified-Release Drug Delivery Systems: Site-Targeted01:24

Modified-Release Drug Delivery Systems: Site-Targeted

Site-targeted drug delivery systems enhance therapeutic efficacy while minimizing systemic toxicity and treatment costs. Unlike conventional methods, these systems ensure precise drug delivery, improving bioavailability and reducing side effects. Targeted drug delivery is classified into three levels. First-order targeting directs drugs to the capillary beds of specific organs or tissues. Second-order targets specific cell types, such as tumor cells, using receptor-mediated interactions.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Redox- and Photo-Responsive Fe<sup>3+/2+</sup>-Cross-Linked Carboxymethyl Cellulose Methacrylate Dissipative Gels: Synthesis and Applications.

ACS applied materials & interfaces·2026
Same author

Tumor Microenvironmental Regulation of CAR T-Cell Therapy in High Risk Medulloblastoma.

Research square·2026
Same author

Solid Pro-Nano Lipid Oral Formulations for Cannabidiol (CBD).

Pharmaceutics·2026
Same author

A critical review of the methodology of ovine lumbar interbody fusion studies and recommendations for future study design.

Bone & joint research·2026
Same author

Injectable Cisplatin-Loaded Biodegradable Poly(anhydride-ester) for Treating Head and Neck Cancer: Preclinical Studies.

ACS biomaterials science & engineering·2026
Same author

Toward FGF2 reduction in cultured meat media: polyphenol salts enhance growth and differentiation of bESC aggregates.

Frontiers in nutrition·2025

Related Experiment Video

Updated: Jul 14, 2026

3D Printing of In Vitro Hydrogel Microcarriers by Alternating Viscous-Inertial Force Jetting
05:32

3D Printing of In Vitro Hydrogel Microcarriers by Alternating Viscous-Inertial Force Jetting

Published on: April 21, 2021

Polymer carriers for drug delivery in tissue engineering.

Marina Sokolsky-Papkov1, Kapil Agashi, Andrew Olaye

  • 1Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

Advanced Drug Delivery Reviews
|June 2, 2007
PubMed
Summary

Tissue engineering offers a promising alternative for transplantation needs by using synthetic polymers for scaffold fabrication. These materials support cell growth and drug delivery for tissue regeneration.

More Related Videos

A Facile and Eco-friendly Route to Fabricate Poly(Lactic Acid) Scaffolds with Graded Pore Size
13:46

A Facile and Eco-friendly Route to Fabricate Poly(Lactic Acid) Scaffolds with Graded Pore Size

Published on: October 17, 2016

Fabrication of Extracellular Matrix-derived Foams and Microcarriers as Tissue-specific Cell Culture and Delivery Platforms
11:19

Fabrication of Extracellular Matrix-derived Foams and Microcarriers as Tissue-specific Cell Culture and Delivery Platforms

Published on: April 11, 2017

Related Experiment Videos

Last Updated: Jul 14, 2026

3D Printing of In Vitro Hydrogel Microcarriers by Alternating Viscous-Inertial Force Jetting
05:32

3D Printing of In Vitro Hydrogel Microcarriers by Alternating Viscous-Inertial Force Jetting

Published on: April 21, 2021

A Facile and Eco-friendly Route to Fabricate Poly(Lactic Acid) Scaffolds with Graded Pore Size
13:46

A Facile and Eco-friendly Route to Fabricate Poly(Lactic Acid) Scaffolds with Graded Pore Size

Published on: October 17, 2016

Fabrication of Extracellular Matrix-derived Foams and Microcarriers as Tissue-specific Cell Culture and Delivery Platforms
11:19

Fabrication of Extracellular Matrix-derived Foams and Microcarriers as Tissue-specific Cell Culture and Delivery Platforms

Published on: April 11, 2017

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Polymer Chemistry

Background:

  • Increasing demand for transplantable tissues and organs exceeds current supply from autogeneic and allogeneic sources.
  • Tissue engineering emerges as a critical alternative, aiming to regenerate or replace damaged tissues.
  • Synthetic polymers are increasingly investigated for their role in tissue engineering scaffolds.

Purpose of the Study:

  • To review the application of synthetic polymers in tissue engineering scaffolds.
  • To discuss the use of these scaffolds for cell and extracellular matrix support.
  • To explore the controlled release of bioactive molecules for tissue regeneration.

Main Methods:

  • Literature review of synthetic polymers used in tissue engineering.
  • Analysis of scaffold properties for cell integration and matrix formation.
  • Evaluation of drug delivery systems integrated into polymer scaffolds.

Main Results:

  • Synthetic polymers offer versatile platforms for fabricating tissue engineering scaffolds.
  • These scaffolds effectively support cell adhesion, proliferation, and extracellular matrix deposition.
  • Incorporation of bioactive molecules into scaffolds enables controlled release, guiding tissue development.

Conclusions:

  • Synthetic polymers are vital biomaterials for advanced tissue engineering applications.
  • Scaffold design utilizing synthetic polymers can significantly enhance tissue regeneration outcomes.
  • Further research into polymer-biomolecule interactions will optimize therapeutic potential.