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Updated: Jul 14, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Blood pressure management in acute ischemic stroke
Kamakshi Lakshminarayan1, David C Anderson, Catherine Borbas
1Department of Neurology, University of Minnesota, Minneapolis, MN 55455, USA. laksh004@umn.edu
Managing hypertension in acute ischemic stroke patients requires improvement. Many patients were overtreated or undertreated in the first 24 hours, despite good management at discharge.
Area of Science:
- Neurology
- Cardiology
- Public Health
Background:
- Hypertension management is critical for acute ischemic stroke patients.
- Guidelines from the American Stroke Association (ASA) and European Stroke Initiative (EUSI) exist for stroke care.
- Variability in provider practice may impact patient outcomes.
Purpose of the Study:
- To characterize provider practice in hypertension management for hospitalized acute ischemic stroke patients.
- To compare current practices against ASA and EUSI guidelines.
- To identify gaps in evidence and areas for improved patient management.
Main Methods:
- Retrospective analysis of data from the Project for Improvement of Stroke Care Management in Minnesota.
- Inclusion of 1181 hospitalized acute ischemic stroke patients.
- Assessment of hypertension treatment (as-needed medication and at discharge) against established guidelines.
Main Results:
- Among 129 patients receiving as-needed medication within 24 hours, 56% were overtreated per ASA guidelines and 24% per EUSI guidelines.
- Of 1052 patients not receiving immediate treatment, 16% were undertreated by ASA guidelines and 3% by EUSI guidelines.
- Discharge hypertension management was effective, with 93% of patients appropriately treated.
Conclusions:
- Significant overtreatment and undertreatment of hypertension occur in the acute phase of ischemic stroke.
- Current hypertension management practices in acute ischemic stroke patients do not consistently align with established guidelines.
- Further research is needed to refine guidelines and reduce practice variability for better stroke patient care.
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