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Right ventricular Tei index in children: effect of method, age, body surface area, and heart rate
1Heart Institute for Children, Hope Children's Hospital, Oak Lawn, Illinois 60453, USA. david@thic.com
Insights
The right ventricular (RV) Tei index (RVTX) differs slightly between Doppler tissue imaging (DTI) and pulse wave Doppler (PWD) methods in children. RVTX is influenced by age and body surface area (BSA), requiring consideration for accurate RV function assessment.
Area of Science:
- Pediatric Cardiology
- Echocardiography
- Cardiac Physiology
Background:
- The right ventricular (RV) Tei index (RVTX) is a valuable tool for assessing global RV systolic and diastolic function.
- Its application spans various pediatric congenital and acquired cardiac conditions.
Purpose of the Study:
- To investigate the influence of Doppler tissue imaging (DTI) versus pulse wave Doppler (PWD) methods on RVTX measurements in children.
- To determine the impact of age, body surface area (BSA), and heart rate on RVTX values.
Main Methods:
- A cross-sectional study involving 308 children with normal echocardiograms.
- RVTX was calculated using both DTI and PWD in each participant.
- Univariate and multivariate regression analyses were performed to assess influencing factors.
Main Results:
- A statistically significant difference was observed between RVTX-DTI (0.37 ± 0.05) and RVTX-PWD (0.34 ± 0.06).
- Age and BSA showed small positive correlations with both RVTX methods, while heart rate exhibited a negative correlation.
- Multivariate analysis revealed BSA as a significant factor for RVTX-DTI and age for RVTX-PWD.
Conclusions:
- The method used for RVTX measurement (DTI vs. PWD) impacts results in pediatric populations.
- Accurate RVTX assessment necessitates considering BSA for DTI measurements and age for PWD measurements.
- These findings are crucial for reliable evaluation of RV function in children.
Abstract:
The right ventricular (RV) Tei index (RVTX) has been used to analyze systolic and diastolic global RV function in various congenital and acquired cardiac abnormalities in children. We conducted a study to determine the effects of the methods of Doppler tissue imaging (DTI) versus pulse wave Doppler (PWD) and age, body surface area (BSA), and heart rate on the RVTX in a population of 308 children with normal echocardiogram findings. Participants ranged in age from 1 day to 18 years, with BSA from 0.08 to 2.4 m2 and heart rate from 46 to 182/min. The RVTX was calculated by both DTI and PWD in each patient during a single echocardiographic examination. RVTX-DTI = 0.37 +/- 0.05 (mean +/- SD) versus RVTX-PWD = 0.34 +/- 0.06 were slightly but statistically different (P < .001). Univariate linear regression analysis showed age and BSA both had small but significant positive effects on both the RVTX-DTI and RVTX-PWD, and heart rate had a small but significant negative effect on both techniques (all with P < .01). By multivariate regression analysis RVTX-DTI was significantly affected only by the BSA and the RVTX-PWD only by age (both with P < .05). Therefore, one must consider the method of RVTX measurement, the BSA for RVTX-DTI, and the age for RVTX-PWD to accurately assess RVTX values.
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