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Understanding the sensitized patient

Ronald H Kerman1

  • 1The University of Texas Medical School, Houston, TX 77030, USA. ronald.h.kerman@uth.tmc.edu

Heart Failure Clinics
|June 5, 2007
PubMed

New technologies have resulted in the ability to identify the presence of IgG human leukocyte antigen (HLA) or non-HLA antibodies in the sera of potential solid organ transplant recipients. Knowledge of the presence of these antibodies, their antigen specificities, and strength (titer) is crucial to understanding a patient's state of immunologic sensitization and reactivity. Finally, these data, when correlated with sensitive crossmatch results, allow clinicians to make more knowledgeable clinical decisions when paring donors and recipients for transplant.

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