[Ultrastrtctural observation of bone marrow stromal cells cultured in coralline hydroxyapatite]
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Updated: Jul 14, 2026
A Three-dimensional Tissue Culture Model to Study Primary Human Bone Marrow and its Malignancies
Published on: March 8, 2014
Xiao-li Tu1, Hong-wei Liu, Yasutomo Iwai
1Department of Stomatology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. renliwn@126.com
Objective:
To observe the ultrastructure of bone marrow stromal cells (BMSCs) cultured in coralline hydroxyapatite (CHA) and evaluate their biocompatibility.
Methods:
BMSCs isolated from dogs were cultured with CHA as the scaffold, and the morphologies of the cells were observed with phase-contrast microscope and scanning electron microscope.
Results And Conclusion:
BMSCs grew well with good attachment to the CHA scaffold and performed normal function, demonstrating CHA as one of useful biocarrier materials for bone tissue engineering.
