Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Methods of Documentation VII: EMR01:30

Methods of Documentation VII: EMR

Electronic Medical Records (EMRs) primarily center around electronically documenting patients' health information within a single healthcare organization or practice. They contain essential clinical data related to a patient's medical history, diagnoses, medications, treatment plans, lab results, and other pertinent information relevant to the specific encounter or episode of care. EMRs are designed to streamline documentation and workflow processes within individual healthcare settings,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevention, Screening, Diagnosis, and Treatment of Iron Deficiency and Iron Deficiency Anemia in Infants, Children, and Adolescents: Clinical Report.

Pediatrics·2026
Same author

Generic and Biosimilar Prescribing in Children and Adolescents: Policy Statement.

Pediatrics·2026
Same author

Generic and Biosimilar Prescribing in Children and Adolescents: Technical Report.

Pediatrics·2026
Same author

Constructing a corpus of hematologic pathology notes for the fine-tuning of BERT models for named entity recognition.

Computers in biology and medicine·2026
Same author

Single source - triple flow: Structured electronic data capture for pancreatic surgery patients.

Digital health·2026
Same author

LEVERAGING EPIC'S NATIVE ETL INFRASTRUCTURE FOR OMOP CDM IMPLEMENTATION: A COLLABORATIVE EXPERIENCE.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2026

Related Experiment Video

Updated: Jul 14, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
05:10

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Published on: December 11, 2016

Electronic prescribing systems in pediatrics: the rationale and functionality requirements.

Robert S Gerstle, Christoph U Lehmann,

    Pediatrics
    |June 5, 2007
    PubMed
    Summary

    Electronic prescribing systems offer benefits for pediatricians in ambulatory settings. Integrating these systems with electronic health records is recommended for improved healthcare delivery.

    Related Experiment Videos

    Last Updated: Jul 14, 2026

    Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
    05:10

    Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

    Published on: December 11, 2016

    Area of Science:

    • Health Informatics
    • Pediatric Healthcare Technology

    Background:

    • Electronic prescribing systems are increasingly important in ambulatory care.
    • Pediatricians face unique challenges and benefits with these systems.

    Purpose of the Study:

    • To discuss the limitations and benefits of electronic prescribing systems for pediatricians.
    • To support policy recommendations for the adoption of electronic prescribing.

    Main Methods:

    • Technical report analysis.
    • Review of electronic prescribing system integration.

    Main Results:

    • Electronic prescribing systems have both limitations and potential benefits.
    • Integration with electronic health records and practice management systems is advantageous.

    Conclusions:

    • Adoption of electronic prescribing should align with a move towards comprehensive electronic health records.
    • Supports pediatrician adoption of electronic prescribing systems.