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[Prevention of side effects of specific chemotherapy in patients with pulmonary tuberculosis]
Abstract:
Data are given related to a combined examination of 168 pulmonary tuberculosis patients in whom immunomodulating T-activin and levamisole chemotherapy was carried out in 40 subjects. In tuberculosis patients with significantly abnormal parameters of the immunity T-system, side effects of the antituberculosis drugs developed in 67.7%, while in those who were subjected to a general scheme of treatment with inclusion of the immunomodulating drugs in only 17.5%. T-activin was found to be highly effective in preventing side effects of the antituberculosis drugs. A diverse influence of the immunity modulating drugs on some T-lymphocyte classes was registered, which is essential in choosing the suitable modulator and regimen of its use.