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An Assay to Detect Protection of the Retinal Vasculature from Diabetes-Related Death in Mice
Published on: January 12, 2024
[Nephropathy and retinopathy in type 1 diabetics assisted by a universitary multiprofessional program]
Emerson Sampaio1, Henriqueta G G Almeida, Vinicius Daher Alvares Delfino
1Ambulatório Multiprofissional de Diabetes, Hospital das Clínicas, Universidade Estadual de Londrina, PR.
Abstract:
Type 1 diabetes mellitus (DM) is linked to micro and macrovascular long-term complications. We proposed to study the association between diabetic nephropathy (DN) and retinopathy (DR), and of these complications with clinical-laboratory variables in type 1 DM patients followed in a universitary center. It was a transversal study through medical registry analysis. We studied 81 patients; prevalence of DR was 21.0% and of DN was 35.8%, there was association between the complications. Carriers of DN and DR have greater DM duration, greater hypertension prevalence, worse glycemic control and greater LDL cholesterol. It was found reduced glomerular filtration rate (GFR) in patients with microvascular complications, mainly in the ones with advanced lesions. In our study there was association between DR, ND and GFR, DM duration and hypertension were independently associated variables.
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