Related Experiment Video
Updated: Jul 14, 2026

07:44
Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
Published on: March 12, 2018
[Skeletal muscle metastases from non small cell lung]
E Faure1, F Le Pimpec-Barthes, D Dusser
1Service de Chirurgie Thoracique, Hôpital Européen Georges Pompidou, Paris, France.
Revue Des Maladies Respiratoires
|June 6, 2007
Summary
Metastatic spread to skeletal muscle from non-small cell lung cancer (NSCLC) is rare. Aggressive local treatment, including surgery and radiation, can provide pain relief despite a poor prognosis.
Area of Science:
- Oncology
- Surgical Oncology
- Radiotherapy
Background:
- Non-small cell lung cancer (NSCLC) is a leading cause of cancer death.
- Metastatic spread to skeletal muscle is an uncommon presentation of NSCLC.
- Skeletal muscle metastases often indicate a poor prognosis.
Observation:
- A patient with inoperable NSCLC presented with a painful right thigh swelling due to metastatic disease.
- The patient underwent muscle resection, radiotherapy, and chemotherapy.
Findings:
- The aggressive local treatment achieved complete pain relief and no local recurrence.
- Despite local control, the patient developed widespread systemic metastases.
- The patient died 11 months post-surgery.
Implications:
- Skeletal muscle metastases from NSCLC, though rare, warrant consideration for aggressive local treatment.
- While prognosis remains poor, multimodal therapy can improve quality of life by managing painful symptoms.
- This case highlights the complex management of advanced NSCLC with unusual metastatic patterns.

