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Related Concept Videos

Pain01:20

Pain

Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
Nociception01:44

Nociception

Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain. Thus, pain helps the...
Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
Blood and Nerve Supply to the Bones01:29

Blood and Nerve Supply to the Bones

Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...

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Related Experiment Video

Updated: Jul 14, 2026

Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams
09:00

Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams

Published on: July 7, 2023

[Physical and psychic elements in chronic pain].

Camilla Callegari, Fabio Salvaggio, Anna Gerlini

    Recenti Progressi in Medicina
    |June 6, 2007
    PubMed
    Summary

    Chronic pain affects both physical and mental health, varying in intensity and presentation across different mental illnesses. Psychiatric medications can offer benefits for managing chronic pain conditions.

    Area of Science:

    • Psychiatry
    • General Medicine
    • Pain Management

    Background:

    • Chronic pain is a prevalent condition impacting both general medicine and psychiatric practices.
    • Pain perception involves complex physical and psychological components.
    • The manifestation of chronic pain, including its role, frequency, and intensity, differs significantly among various mental illnesses.

    Discussion:

    • The interplay between chronic pain and mental health conditions necessitates integrated treatment approaches.
    • Understanding the unique pain profiles in psychiatric disorders is crucial for effective management.
    • Psychiatric drugs demonstrate potential utility in alleviating chronic pain symptoms.

    Key Insights:

    • Chronic pain presents with both physical and psychic dimensions.

    More Related Videos

    A Protocol of Manual Tests to Measure Sensation and Pain in Humans
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    A Protocol of Manual Tests to Measure Sensation and Pain in Humans

    Published on: December 19, 2016

    Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing
    09:16

    Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing

    Published on: February 16, 2017

    Related Experiment Videos

    Last Updated: Jul 14, 2026

    Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams
    09:00

    Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams

    Published on: July 7, 2023

    A Protocol of Manual Tests to Measure Sensation and Pain in Humans
    07:28

    A Protocol of Manual Tests to Measure Sensation and Pain in Humans

    Published on: December 19, 2016

    Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing
    09:16

    Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing

    Published on: February 16, 2017

  • Mental illness influences the characteristics of chronic pain.
  • Pharmacological interventions from psychiatry can aid in chronic pain treatment.

    • Outlook:

    • Further research into the neurobiological underpinnings of pain in psychiatric disorders is warranted.
    • Developing targeted psychiatric treatments for chronic pain subtypes could improve patient outcomes.
    • Enhanced collaboration between pain specialists and psychiatrists is essential for holistic patient care.