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Related Experiment Videos

eFSH in clinical equine practice.

P M McCue1, M M LeBlanc, E L Squires

  • 1Colorado State University, Ft. Collins, CO 80523, and Rood and Riddle Equine Hospital, Lexington, KY 40580, United States. pmccue@colostate.edu

Theriogenology
|June 6, 2007
PubMed
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This study details an effective equine follicle stimulating hormone (eFSH) protocol for inducing follicular development and ovulation in mares. The optimized eFSH treatment, combined with prostaglandins and human chorionic gonadotropin, enhances reproductive efficiency in mares.

Area of Science:

  • Veterinary Medicine
  • Reproductive Endocrinology
  • Equine Science

Background:

  • Equine follicle stimulating hormone (eFSH) is crucial for follicular development in mares.
  • Previous protocols have shown variable success in inducing ovulation, particularly in mares with reproductive challenges.

Purpose of the Study:

  • To define an optimized protocol for using eFSH to induce follicular development and ovulation in mares.
  • To improve reproductive outcomes in transitional, acyclic, and cycling mares.

Main Methods:

  • Administering 12.5 mg eFSH intramuscularly twice daily, starting 5-7 days post-ovulation when the largest follicle measures 20-25 mm.
  • Administering prostaglandins on the second day of eFSH therapy.
  • Continuing eFSH treatment for 3-5 days until follicles reach ≥35 mm, followed by a 36-hour 'coasting' period and human chorionic gonadotropin administration for ovulation induction.

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Main Results:

  • The described protocol effectively stimulates follicular development to ≥35 mm.
  • This method facilitates ovulation induction through a timed hormonal sequence.

Conclusions:

  • The established eFSH protocol provides a reliable method for managing follicular development and inducing ovulation in diverse equine reproductive scenarios.
  • This optimized treatment enhances the potential for successful breeding in mares.