Basilar membrane mechanics in the 6-9 kHz region of sensitive chinchilla cochleae

The vibration of the basilar membrane in the 6-9 kHz region in the chinchilla cochlea has been studied using a displacement sensitive interferometer. Displacements of 0.7-1.4 nm at 0 dB sound pressure level have been obtained. At the characteristic frequency (CF), rate-of-growth (ROG) functions computed as the slope of input-output (IO) functions can be as low as 0.1 dB/dB. IO functions for frequencies > CF have ROGs near 0 dB/dB and can have notches characterized by both negative slopes and expansive ROGs, i.e., > 1 dB/dB. For frequencies < 0.6*CF, ROGs > 1.2 dB/dB were found. Cochlear gain is shown to be greater than 60 dB in sensitive preparations with a single cochlea having nearly 80 dB gain. The compressive nature of the cochlea remains at all levels though it is masked at frequencies > CF when the amplitude of a compression wave exceeds that of the traveling wave. The compression wave produces the plateau region of the mechanical response at high intensities and has a nearly constant phase versus frequency function implying a high velocity. The summation of the traveling and compression waves explains the occurrence of the notches in both the IO and iso-intensity functions. Vibration of the osseous spiral limbus may alter the drive to inner hair cells.