Related Experiment Video
Updated: Jul 14, 2026

07:16
Three-Dimensional Imaging of Tumor-Bearing Tissue Using the Iterative Bleaching Extends Multiplexity Approach
Published on: April 25, 2025
[Tumors and tumor-like lesions]
S Kösling1, S Knipping, D Stoevesandt
1Klinik für Diagnostische Radiologie, Martin-Luther-Universität Halle-Wittenberg, Halle. sabrina.koesling@medizin.uni-halle.de
Der Radiologe
|June 7, 2007
Summary
Paranasal sinus tumors, though rare, have diverse histology but limited imaging patterns. CT and MRI are crucial for assessing tumor extent and guiding treatment planning for these sinonasal lesions.
Area of Science:
- Radiology
- Otolaryngology
- Pathology
Background:
- Paranasal sinus tumors and tumor-like lesions are uncommon, presenting a wide range of histological subtypes.
- Imaging modalities reveal limited morphological patterns despite histological diversity.
- Accurate histological diagnosis is vital for effective therapeutic strategies.
Purpose of the Study:
- To evaluate the capabilities and constraints of computed tomography (CT) and magnetic resonance imaging (MRI).
- To assess the dignity and extent of paranasal tumors and tumor-like lesions.
- To provide imaging features of various paranasal tumors for therapeutic planning.
Main Methods:
- Review of CT and MRI findings in paranasal sinus lesions.
- Correlation of imaging features with histological diagnoses.
- Discussion of imaging's role in determining lesion spread and aiding therapeutic decisions.
Main Results:
- CT and MRI offer valuable insights into the extent and spread of paranasal lesions.
- Imaging characteristics can suggest the nature (benign vs. malignant) of sinonasal masses.
- Histological sampling remains essential for definitive diagnosis and treatment planning.
Conclusions:
- Imaging, particularly CT and MRI, plays a critical role in evaluating paranasal sinus tumors and tumor-like lesions.
- Understanding imaging features aids in differentiating lesion types and assessing their spread.
- Integrated approach of imaging and histology is necessary for optimal management of sinonasal diseases.
Related Concept Videos
The Tumor Microenvironment
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
The Tumor Microenvironment
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
Tumor Progression
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Tumor Immunotherapy
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
Abnormal Proliferation
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Abnormal Proliferation
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
