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[A clinical study on renal cell carcinoma]
M Yanagawa1, S Suzuki, K Kameda
1Department of Urology, Mie University School of Medicine.
Hinyokika Kiyo. Acta Urologica Japonica
|October 1, 1991
Summary
This study on renal cell carcinoma (RCC) found that lymph node and distant metastasis significantly impact survival rates. While therapies showed varied effects, VBL therapy demonstrated a beneficial outcome for RCC patients.
Area of Science:
- Oncology
- Urology
- Medical Statistics
Context:
- Retrospective analysis of 95 renal cell carcinoma (RCC) patients from 1973-1988.
- Demographic data: Male to female ratio 3:1, average age 61.
- Common presenting symptoms: Hematuria (46.3%) and incidental findings (18.9%).
Purpose:
- To analyze survival rates and prognostic factors in renal cell carcinoma (RCC).
- To evaluate the impact of metastasis, cell type, and therapeutic interventions on patient outcomes.
Summary:
- Overall 5- and 10-year survival rates for RCC were 51.9% and 37.1%.
- Five-year survival rates varied significantly by stage: Stage I (82.7%), II (54.7%), III (20.0%), IV (4.7%).
- Lymph node and distant metastasis were significant negative prognostic factors (p<0.01); cell type and renal vein involvement were not significant.
Impact:
- Identifies key prognostic indicators for renal cell carcinoma (RCC), aiding in risk stratification.
- Suggests potential benefits of VBL therapy, warranting further investigation.
- Provides historical data on RCC survival and treatment outcomes for comparison with contemporary practices.