Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...

Peritoneal Dialysis I: Introduction and Procedure

Peritoneal Dialysis I: Introduction and Procedure

Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...

Hemodialysis I: Introduction

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...

Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis

Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis

Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...

Hemodialysis II: Procedure and Complications

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...

Dialysis

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Relationship between the amount of copper and zinc given to critically ill patients on total parenteral nutrition and plasma and erythrocyte copper and zinc levels].

Nutricion hospitalaria·2008

Same author

[The Italian nephrology network: findings and indications of the Italian Society of Nephrology (SIN)].

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia·2008

Same author

[Quality certification project for chronic renal failure management].

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia·2008

Same author

GIT (Glucose Infusion Test): polycentric evaluation of a new test for vascular access recirculation.

The journal of vascular access·2007

Same author

[2004 census of the Italian nephrology and dialysis units].

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia·2007

Same author

[Withdrawing or discontinuing chronic dialysis in adult patients].

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia·2007

Search research articles

Related Experiment Video

Updated: Jul 14, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

[1966: an automatic peritoneal dialysis machine. A personal experience].

¹U.B. di Nefrologia e Dialisi, Ospedale della Valle D'Aosta, Aosta - Italy.

Giornale Italiano Di Nefrologia : Organo Ufficiale Della Societa Italiana Di Nefrologia

|June 8, 2007

Summary

A custom peritoneal dialysis machine was developed in 1966 to speed up treatments. This innovation significantly improved urea clearance, enhancing patient care for acute and chronic kidney failure.

More Related Videos

Laparoscopic-Assisted Seldinger Technique for Peritoneal Dialysis Catheter Insertion

Laparoscopic-Assisted Seldinger Technique for Peritoneal Dialysis Catheter Insertion

Published on: May 23, 2025

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

Related Experiment Videos

Last Updated: Jul 14, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

Laparoscopic-Assisted Seldinger Technique for Peritoneal Dialysis Catheter Insertion

Laparoscopic-Assisted Seldinger Technique for Peritoneal Dialysis Catheter Insertion

Published on: May 23, 2025

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

Area of Science:

Nephrology
Medical Engineering

Context:

Peritoneal dialysis is a crucial treatment for renal failure.
Early dialysis machines required significant time for treatment cycles.

Purpose:

To develop a functional "rapid-exchange" peritoneal dialysis machine based on Boen's model.
To improve the efficiency and effectiveness of peritoneal dialysis treatments.

Summary:

A self-made peritoneal dialysis machine was constructed in 1966 at the University of Turin.
The machine utilized three timers and optimized inflow/outflow phases for rapid exchange.
A mechanical recorder tracked outflow curves for monitoring treatment.

Impact:

Rapid-exchange peritoneal dialysis increased urea clearance from 18 to 34 mL/min.
This advancement improved treatment outcomes for patients with acute and chronic renal failure.