Related Experiment Video
Updated: Jul 14, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
Published on: July 20, 2022
[1966: an automatic peritoneal dialysis machine. A personal experience]
1U.B. di Nefrologia e Dialisi, Ospedale della Valle D'Aosta, Aosta - Italy.
Abstract:
In 1966 a self-made peritoneal dialysis machine according to Boen's model was built at the Nephrology Unit of the University of Turin (Italy) to facilitate the conduction of "rapid-exchange" peritoneal dialysis. Three timers controlled the dialysate inflow, dwell and outflow phases. Inflow and outflow times were reduced by means of wide dialysate lines and negative pressure in the drainage reservoir. A mechanical recorder registered the outflow curves. With rapid-exchange peritoneal dialysis, urea clearance increased from 18 to 34 mL/min, thereby improving the treatment of both acute and chronic renal failure patients.
Related Concept Videos
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Peritoneal Dialysis I: Introduction and Procedure
Hemodialysis I: Introduction
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis
Hemodialysis II: Procedure and Complications
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...

