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Published on: March 8, 2019
Pulmonary manifestations of Pyoderma gangrenosum
Bachar Chahine1, Cecile Chenivesse, Isabelle Tillie-Leblond
1Service de pneumologie et immuno-allergologie, Hôpital universitaire Calmette, Lille. bacharchahine@hotmail.com
Introduction:
Pyoderma gangrenosum is an uncommon ulcerative cutaneous disorder. Extracutaneous localizations are rare. Respiratory system involvement has been described in a few cases, but the pulmonary features reported were highly variable.
Case:
We report two cases of patients with Pyoderma gangrenosum combining cutaneous and pulmonary manifestations. One case presented multiple nodular lesions, some with cavitation. The underlying disease was varicella-zoster virus infection. The second presented pneumonitis with bronchiolar micronodules.
Discussion:
Few cases have reported Pyoderma gangrenosum with pulmonary involvement, which appears to be manifested mainly as nodules or interstitial lung disease. The principal differential diagnosis is Wegener's granulomatosis.
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