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Updated: Jul 14, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Does left atrial appendage peak emptying flow velocity predict the electrical energy required to achieve successful
Rowlens M Melduni1, Krishnaswamy Chandrasekaran, Paul A Friedman
1Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA. melduni.rowlens@mayo.edu <melduni.rowlens@mayo.edu>
Background:
The relation of left atrial (LA) appendage peak emptying flow velocity (LAAEV) with energy requirement for successful direct-current cardioversion (DCCV) in persistent atrial fibrillation (AF) is unknown. LAAEV correlates with success of cardioversion of AF to sinus rhythm, both of which are related to the LA size and the chronicity of AF. We tested the hypothesis that LAAEV can predict optimal energy required for DCCV in persistent AF (>48 hours).
Methods:
We studied 1050 consecutive patients with persistent AF who underwent successful transesophageal echocardiographically guided DCCV from 2000 to 2005. After excluding patients with atrial flutter and those receiving antiarrhythmic drugs, 454 patients qualified for the study.
Results:
LAAEV did not correlate with cardioversion energy (r = 0.06, P = .23) or number of shocks required for successful DCCV (r = 0.05, P = .33). The only predictor of energy required for successful cardioversion was the chronicity of AF.
Conclusion:
LAAEV does not predict electrical energy required for successful cardioversion in persistent AF.

