Related Experiment Video
Updated: Jul 14, 2026

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
Published on: February 22, 2019
Predicting pertussis in a pediatric emergency department population
Jennifer E Mackey1, Susan Wojcik, Ray Long
1The Department of Emergency Medicine, University of New York Upstate Medical University, Syracuse, NY 13210, USA. mackeyj@upstate.edu
Pertussis (whooping cough) is surging in infants. Infants under 2 months with specific cough, choking, cyanosis, and rhonchi symptoms are highly likely to have pertussis.
Area of Science:
- Pediatric Emergency Medicine
- Infectious Diseases
- Public Health
Background:
- Pertussis (whooping cough) is a serious respiratory illness with cases at a 40-year high, particularly affecting infants.
- Pediatric emergency departments are common sites for initial pertussis evaluation.
- Early recognition is crucial for rapid triage, isolation, and preventing hospital-acquired (nosocomial) transmission.
Purpose of the Study:
- To identify key clinical predictors of pertussis in pediatric emergency department patients.
- To enable prompt identification and isolation of infants with pertussis to prevent transmission.
Main Methods:
- Retrospective, case-control chart review of pediatric patients (0-18 years) presenting to the emergency department.
- Analysis of medical history and physical examination variables to predict pertussis, confirmed by laboratory testing.
Main Results:
- Infants younger than 2 months presenting with cough or choking, cyanosis, and rhonchi on examination showed a high likelihood of pertussis.
- These specific clinical signs are strong predictors for pertussis in young infants.
Conclusions:
- Prompt identification of pertussis in infants under 2 months presenting with specific symptoms is critical in the emergency department.
- Immediate isolation and testing of these infants can lead to timely treatment and reduce nosocomial transmission within the department.
Related Concept Videos
Respiratory Syncytial Virus Disease
Steps in Outbreak Investigation
Pneumonia III: Complications and Assessment
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Transmission-based Precautions I: Contact, Enteric, and Droplets
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Infectious Diseases and Their Occurrence
