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Plasmodium p25 and p28 surface proteins: potential transmission-blocking vaccines

Ajay K Saxena1, Yimin Wu, David N Garboczi

  • 1School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India. ajaysaxena@mail.jnu.ac.in

Eukaryotic Cell
|June 15, 2007
PubMed
Abstract

No abstract available in PubMed .

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Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...

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