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Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
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Haplotype-specific amplification and nucleotide sequencing reveal the novel allele HLA-B*080104

B Eiz-Vesper1, R Blasczyk, P A Horn

  • 1Institute for Transfusion Medicine, Hannover Medical School, Carl-Neuberg-Street 1, 30625 Hannover, Germany.

Tissue Antigens
|June 15, 2007
PubMed

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Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...