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Osmotic Pump-based Drug-delivery for In Vivo Remyelination Research on the Central Nervous System
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Solubility-modulated monolithic osmotic pump tablet for atenolol delivery

Longxiao Liu1, Xiaocui Wang

  • 1Zhejiang University, College of Pharmaceutical Sciences, Hangzhou, People's Republic of China. liulx@zju.edu.cn

European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V
|June 15, 2007
PubMed
Summary

This study developed an acid-modulated monolithic osmotic pump tablet for atenolol delivery. The optimized formulation achieved near zero-order drug release for 24 hours, independent of external conditions.

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