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Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice
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Published on: November 16, 2011

[Hyperinsulinemia and aging]

Tohru Minamino1, Issei Komuro

  • 1Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|June 15, 2007
PubMed
Summary

Genetic mutations can extend lifespan by altering endocrine signaling, particularly the insulin pathway. This review explores how these conserved mechanisms in animals relate to aging, diabetes, and longevity.

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