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Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants
Published on: August 5, 2021
Surface modification of titanium implants using bioactive glasses with air abrasion technologies
Garrit Koller1, Richard J Cook, Ian D Thompson
1Biomaterials and Biomimetics, King's College London, Floor 17, Guy's Tower, Guy's Hospital, St Thomas' St, London SE1 9RT, UK. garrit.koller@kcl.ac.uk
Journal of Materials Science. Materials in Medicine
|June 15, 2007
Summary
Bioactive glass 45S5 abrasive blasting creates a rough titanium surface for better bone integration in dental and orthopedic implants. This osteoproductive coating enhances osseous tissue integration, benefiting surgical outcomes.
Area of Science:
- Biomaterials Engineering
- Surface Science
- Orthopaedic Research
Background:
- Surface modification of titanium implants is crucial for osseous tissue integration in dental and orthopaedic surgery.
- Current surface treatments aim to enhance implant-device biological interaction.
- Exploring novel osteoproductive materials is essential for improving implant efficacy.
Purpose of the Study:
- To investigate bioactive glass 45S5 as an abrasive and osteoproductive surface modification for titanium implants.
- To characterize the surface roughness and bioactive glass distribution on modified titanium.
- To assess the potential of bioactive glass 45S5 for enhancing osseous integration.
Main Methods:
- Abrasive blasting of commercially pure titanium using bioactive glass 45S5.
- Surface roughness analysis using white light interferometry (quantifying S(a)).
- Surface composition and morphology analysis via Energy Dispersive X-ray Analysis (EDXA) and electron microscopy.
Main Results:
- Abrasive blasting produced an irregular titanium surface with a surface roughness average (S(a)) of 1.1 microm.
- Bioactive glass 45S5 was uniformly distributed across the titanium surface and within surface features.
- The achieved surface roughness is comparable to existing implant designs.
Conclusions:
- Bioactive glass 45S5 is a viable material for abrasive surface modification of titanium.
- The modified titanium surfaces exhibit characteristics favorable for osseous tissue integration.
- This surface treatment holds promise for improving the success of dental and orthopaedic implants.
