Related Experiment Video
Updated: Jul 14, 2026

Purification of Transcripts and Metabolites from Drosophila Heads
Published on: March 15, 2013
From genomics to mechanistic insight: a global perspective on molecular deficits induced by environmental agents
Kenneth S Ramos1, Marlene C Steffen, M H Falahatpisheh
1Department of Biochemistry and Molecular Biology, University of Louisville School of Medicine, University of Louisville, Louisville, Kentucky 40202, USA. ksramo01@luisville.edu
Abstract:
As the postgenomic era continues to unfold, a new wave of scientific investigation is upon us focusing on the application of genomic technologies to study the meanings encrypted on the DNA code and the responses of living organisms to changes in their environment. Recent functional genomics studies in this laboratory have focused on the role of the aryl hydrocarbon receptor, a ubiquitous transcription factor, in genetic programming during renal development. Also of interest is the application of genomics investigations to the study of chronic medical conditions associated with early life exposures to environmental contaminants. Molecular evidence is discussed in this review within the framework of human molecular medicine.
Related Concept Videos
Pharmacogenetics and Pharmacogenomics: Overview
Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...
Pharmacogenomics: Identification of New Drug Targets
Gene-Environment Interactions
Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu
Background and Environment Affect Phenotype
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
