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Advancing Precision-Based, Integrative, and Individualized Health Care in Puerto Rico.

Kenneth S Ramos^1,2,3,4,5, Marianyoly Ortiz-Ortiz⁶, Amarilys Silva-Boschetti⁷

¹Distinguished Professor of Translational Medical Sciences and Alkek Chair of Medical Genetics, Texas A&M University System, College Station, TX, USA.

NEJM Catalyst Innovations in Care Delivery

|July 15, 2026

Summary

Puerto Rico can advance precision medicine by enhancing genomic infrastructure, education, and culturally responsive care. These strategies address chronic diseases and health disparities for better health outcomes.

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Published on: January 12, 2018

Area of Science:

Genomics and personalized healthcare
Health equity and infrastructure development
Public health strategies in diverse populations

Background:

Puerto Rico experiences a high burden of chronic diseases, an aging demographic, and a fragmented healthcare system.
These factors present significant challenges but also highlight the need and opportunity for precision medicine adoption.
Existing health disparities necessitate tailored approaches for effective healthcare delivery.

Purpose of the Study:

To summarize key insights and strategies from a symposium focused on advancing precision medicine in Puerto Rico.
To identify actionable recommendations for scaling precision medicine across the island.
To provide a framework for other resource-constrained health systems.

Main Methods:

Convening cross-sector leaders to discuss and identify strategies for precision medicine implementation.
Synthesizing recommendations from symposium participants.
Analyzing the specific needs and context of Puerto Rico's health system.

Main Results:

Strengthening genomic and digital health infrastructure is crucial.
Aligning reimbursement and regulatory policies is essential for scalability.
Expanding education for clinicians and patients is a key recommendation.
Integrating culturally responsive care models is vital for equitable implementation.

Conclusions:

A multi-faceted approach is required to advance precision medicine in Puerto Rico.
The proposed strategies offer a roadmap for improving healthcare delivery and addressing health disparities.
Lessons learned in Puerto Rico can inform precision medicine initiatives in similar global health settings.