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Updated: Jul 14, 2026

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.
Published on: November 7, 2018
The importance of testing whole stool for Shiga toxin: a clinical and microbiological perspective
Zainab A Malik1, Darcy Broughel
1Department of Pediatrics, Division of Pediatric Infectious Diseases, Montefiore Medical Center, Rosenthal 4, 111 E, 210th Street, Bronx, NY 10467, USA.
Abstract:
This case report emphasizes the importance of testing whole stool for the presence of Shiga toxin; especially in light of clinical suspicion, or whenever a grossly bloody stool specimen is received in the lab. Since organisms other than Escherichia coli O157:H7 can elaborate Shiga toxin, a negative stool culture for the usual enteric pathogens does not rule out the possibility of a Shiga toxin-mediated pathology in the appropriate clinical setting. The presence of this toxin in stool influences a physician's approach towards the patient's antimicrobial management.
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