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Related Concept Videos

Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...

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Related Experiment Video

Updated: Jul 14, 2026

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
07:56

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats

Published on: April 21, 2017

[Major neonatal aortic thrombosis: a case report].

S Nouri1, N Mahdhaoui, S Beizig

  • 1Service de néonatologie, CHU Farhat-Hached, avenue Ibn-El-Jazzar, 4000 Sousse, Tunisie. soniamerchaoui@yahoo.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|June 19, 2007
PubMed
Summary

Neonatal aortic thrombosis, a rare condition, can present with unusual symptoms like kidney failure rather than leg ischemia. Prompt diagnosis and treatment with anticoagulation and thrombolysis led to successful resolution.

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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
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Last Updated: Jul 14, 2026

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
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Published on: April 21, 2017

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Area of Science:

  • Neonatal medicine
  • Pediatric cardiology
  • Vascular medicine

Background:

  • Aortic thrombosis in neonates is uncommon and typically presents with lower limb ischemia.
  • Early diagnosis and intervention are crucial for managing this severe condition.

Observation:

  • A 10-day-old infant presented with renal failure, hematuria, and dehydration, indicative of major aortic thrombosis.
  • Hypertension in the upper limbs was noted, but there were no signs of lower limb ischemia.

Findings:

  • Renal Doppler ultrasound confirmed the diagnosis of aortic thrombosis.
  • The infant's condition resolved following thrombolytic therapy and heparin anticoagulation.

Implications:

  • This case highlights that neonatal aortic thrombosis can manifest with atypical symptoms, emphasizing the need for a broad differential diagnosis.
  • Effective management strategies include prompt diagnosis and combined thrombolytic and anticoagulant therapy.