Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Computer-aided detection for radiological disease severity classification on chest radiograph in children with intra-thoracic tuberculosis.

PLOS global public health·2026
Same author

Complicated tuberculous pleural disease in children.

Paediatric respiratory reviews·2026
Same author

Improving Diagnosis of Severe Paediatric Lymphobronchial Tuberculosis Using Segmentation and Deep Learning on Chest X-Rays.

Respiration; international review of thoracic diseases·2026
Same author

Clinical Evaluation of Pediatric Pulse Oximeters in South Africa: Protocol for a Cluster Randomized Controlled Trial.

JMIR research protocols·2026
Same author

Pulmonary hydatid disease in children: a neglected burden hidden in plain sight.

The Lancet. Respiratory medicine·2026
Same author

Clinical evaluation of pediatric pulse oximeters in South Africa: cluster randomized controlled trial protocol.

JMIR research protocols·2026

Related Experiment Video

Updated: Jul 14, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
10:10

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

Published on: October 5, 2015

Airway involvement in pulmonary tuberculosis.

Pierre Goussard1, Robert Gie

  • 1Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Tygerberg, South Africa. pgouss@sun.ac.za

Paediatric Respiratory Reviews
|June 19, 2007
PubMed
Summary

Lymph gland involvement in children with pulmonary tuberculosis can cause airway obstruction. Treatment involves anti-tuberculosis drugs, corticosteroids, and sometimes surgery for severe cases.

More Related Videos

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Related Experiment Videos

Last Updated: Jul 14, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
10:10

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

Published on: October 5, 2015

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Area of Science:

  • Pediatric Pulmonology
  • Infectious Diseases
  • Thoracic Surgery

Background:

  • Lymph gland involvement of the airways, or lymphobronchial tuberculosis, is a common complication in children with pulmonary tuberculosis.
  • This condition can lead to significant airway obstruction in affected children.

Purpose of the Study:

  • To outline the diagnostic and management strategies for lymphobronchial tuberculosis in children.
  • To identify indications for surgical intervention in cases of persistent airway obstruction.

Main Methods:

  • Assessment primarily involves fibreoptic bronchoscopy.
  • Standard anti-tuberculosis regimens are used, supplemented with a one-month course of corticosteroids, followed by a one-month weaning period.
  • Re-evaluation with bronchoscopy and chest computed tomography is recommended for persistent symptoms.

Main Results:

  • Most children respond to medical management with anti-tuberculosis drugs and corticosteroids.
  • A subset of children with persistent severe airway obstruction may require surgical intervention.
  • Surgical options include endoscopic or transthoracic enucleation of lymph nodes.

Conclusions:

  • Lymphobronchial tuberculosis requires a stepwise approach to management, prioritizing medical therapy.
  • Surgical intervention is reserved for a small percentage of patients with severe, refractory airway obstruction.
  • Early and accurate diagnosis through bronchoscopy is crucial for effective management.