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Updated: Jun 30, 2026

Establishment of a Rat Model of Superior Sagittal-Sinus Occlusion via a Thread-Embolism Method
Published on: July 4, 2021
Thrombosis of sinus sagitalis during puerperium caused by thrombophilic gene mutation
Marina Titlic1, Sanda Pavelin, Ante Tonkic
1Department of Neurology, Split University Hospital, Spincićeva 1, Split 21 000, Croatia. marina.titlic@gmail.com
Abstract:
Cerebral veno-sinus thrombosis (CVT) during puerperium may have fatal consequences. A nonspecific clinical picture must be complete with computed tomography of the brain and digital substract angiography of the brain blood vessels, and, once the clinical diagnosis is confirmed, coagulation tests and genetic analysis of the coagulation factor are to be made as well. Genetic polymorphisms associated with thrombophilia such as factor V Leiden, prothrombin G20210A, MTHFR C677T, ACE and PIA1/A2 may be the cause of the hypercoagulability that results in CVT.
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