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[Toxic megacolon and jejunal perforation due to cytomegalovirus]

Rosa María Jiménez Rodríguez1, Antonio Manuel Puppo Moreno, Javier Salgado Algarrada

  • 1Servicio de Cirugía General, Hospital Universitario Virgen del Rocío, Sevilla, Spain. ros_j_r@hotmail.com

Cirugia Espanola
|June 21, 2007
PubMed

Insights

Cytomegalovirus (CMV) infection commonly causes colitis in immunocompromised patients. This case highlights a rare instance of jejunal perforation due to CMV, successfully treated with surgery and antivirals.

Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Transplant Medicine

Background:

  • Cytomegalovirus (CMV) infection is a significant opportunistic infection in immunocompromised individuals.
  • Gastrointestinal involvement, particularly CMV colitis, is common in this patient population.
  • While CMV colitis is well-documented, complications like jejunal perforation are exceptionally rare.

Observation:

  • A case study involving an immunocompromised patient presenting with bowel perforation.
  • The patient was diagnosed with cytomegalovirus colitis following the perforation event.
  • The clinical presentation involved a rare manifestation of CMV infection in the gastrointestinal tract.

Findings:

  • The patient experienced a perforated jejunum, a rare complication of CMV infection.
  • Diagnosis was confirmed as cytomegalovirus colitis post-bowel perforation.
  • Successful management was achieved through surgical intervention and antiviral therapy.

Implications:

  • This case underscores the potential for severe, uncommon gastrointestinal complications from CMV in immunocompromised hosts.
  • Highlights the importance of considering CMV in the differential diagnosis of bowel perforation in this demographic.
  • Demonstrates the efficacy of a combined surgical and antiviral approach for managing such rare presentations.

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