Related Experiment Video
Updated: Jul 14, 2026
05:39
Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
[Papillary and follicular thyroid carcinoma]
1Service de médecine nucléaire, institut Gustave-Roussy, 39, rue Camille-Desmoulins, 94805 Villejuif cedex, France. schlumbg@igr.fr
Annales D'Endocrinologie
|June 22, 2007
Summary
Thyroid cancer, often found as a nodule, is typically treated with surgery and radioiodine therapy. Most patients with differentiated thyroid carcinomas achieve a cure with proper management and follow-up.
Area of Science:
- Endocrinology
- Oncology
- Pathology
Context:
- Differentiated thyroid carcinomas, including papillary and follicular types, originate from follicular epithelium.
- Increased incidence is linked to enhanced screening methods.
- Thyroid carcinoma commonly presents as a thyroid nodule, with malignancy in only 5% of cases.
Purpose:
- To outline the diagnostic and therapeutic strategies for differentiated thyroid carcinomas.
- To describe the management of thyroid nodules and the treatment protocols for thyroid cancer.
Summary:
- Fine needle biopsy is the primary diagnostic tool for thyroid nodules.
- Standard treatment involves total thyroidectomy with central lymph node dissection for papillary carcinoma, followed by radioiodine therapy for high-risk cases or incomplete resection.
- Surgery alone may suffice for small, unifocal, intra-thyroid papillary carcinomas, while thyroxine treatment is universal.
Impact:
- The majority of patients achieve cure, confirmed by undetectable serum thyroglobulin and normal neck ultrasonography at one year.
- Long-term follow-up includes annual serum thyroglobulin and TSH measurements.
- Management strategies aim to optimize patient outcomes and minimize recurrence risk.
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