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Related Concept Videos

Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Hypersensitivity Reactions: Delayed Hypersensitivity Reactions01:29

Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Type I Diabetes I: Introduction01:12

Type I Diabetes I: Introduction

Type 1 diabetes mellitus is a chronic metabolic disorder characterized by an absolute deficiency of insulin resulting from the autoimmune destruction of pancreatic β-cells. Although it can occur at any age, it is most commonly diagnosed in childhood, adolescence, or early adulthood. The loss of insulin production impairs cellular glucose uptake, resulting in persistent hyperglycemia and necessitating lifelong insulin therapy.Autoimmune Destruction of β-CellsThe hallmark of type 1 diabetes is an...
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...

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Proteins Responsible for Fruit allergies in the Northwest of Spain.

Journal of investigational allergology & clinical immunology·2016
Same author

Anaphylaxis mediated by thaumatin-like proteins.

Journal of investigational allergology & clinical immunology·2015
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Proteins responsible for nut allergies.

Journal of investigational allergology & clinical immunology·2014
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Cat sensitization provoking asthma and pulmonary infiltrates with eosinophilia.

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Exercise-induced anaphylaxis: inhibition with sodium bicarbonate.

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[Hereditary angioneurotic edema].

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Related Experiment Video

Updated: Jul 14, 2026

Induction and Monitoring of Active Delayed Type Hypersensitivity (DTH) in Rats
13:26

Induction and Monitoring of Active Delayed Type Hypersensitivity (DTH) in Rats

Published on: July 19, 2007

Type I latex allergy: a follow-up study.

J Azofra García1

  • 1Department of Allergology, Hospital Central de Asturias, Oviedo, Spain. alergis@hca.es

Journal of Investigational Allergology & Clinical Immunology
|June 23, 2007
PubMed
Summary

Patients with latex allergy often avoid latex in healthcare settings, but non-occupational exposures still cause allergic reactions. Many patients experience symptoms from latex-related foods and other sources, highlighting the need for comprehensive avoidance strategies.

Area of Science:

  • Immunology
  • Allergy and Immunology
  • Public Health

Background:

  • Occupational latex allergy is well-studied, but non-occupational latex allergy evolution remains underexplored.
  • Immunoglobulin E (IgE)-mediated allergy to latex can cause rhinitis and asthma.

Purpose of the Study:

  • To assess patient adherence to latex avoidance measures.
  • To determine the frequency and types of symptoms resulting from latex exposure in healthcare and other settings.

Main Methods:

  • Retrospective study of 23 patients diagnosed with latex allergy over 11 years.
  • Patients were informed about latex avoidance, particularly in surgical, gynecological, and dental settings.

Main Results:

  • Most patients successfully avoided latex in healthcare settings, though one experienced angioedema due to non-disclosure.

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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

Related Experiment Videos

Last Updated: Jul 14, 2026

Induction and Monitoring of Active Delayed Type Hypersensitivity (DTH) in Rats
13:26

Induction and Monitoring of Active Delayed Type Hypersensitivity (DTH) in Rats

Published on: July 19, 2007

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

  • 30% of patients had allergic reactions from other exposures (gloves, balloons, hospital environments).
  • 17% of patients experienced allergic reactions to latex-related foods.
  • Conclusions:

    • While patients generally inform healthcare providers about latex allergy, non-occupational exposures remain a significant issue.
    • Latex-related food allergies and reactions to environmental latex are common, necessitating broader awareness and avoidance.