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Updated: Jul 14, 2026

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
Published on: March 12, 2016
The loss of visual function in glaucoma
P A Sample1, C F Bosworth, R N Weinreb
1Department of Ophthalmology, Glaucoma Center and Visual Function Laboratory, University of California, San Diego, La Jolla, CA 92093-0946, USA. psample@eyecenter.ucsd.edu
Abstract:
This article reviews innovative techniques for assessing the visual field and for examining glaucoma patients for evidence of visual field progression. The authors discuss the algorithms for assessing change in visual fields used in each of several multicenter studies sponsored by the National Eye Institute. The authors also give a brief review of 2 currently available alternatives to standard automated perimetry. Both are visual function specific tests that attempt to evaluate a subpopulation of retinal ganglion cells. Shortwavelength automated perimetry isolates the small bistratified (blue-yellow) ganglion cells, and Frequency Doubling Technology Perimetry tests functions that should be primarily handled by the magnocellular ganglion cells. These new perimetric procedures are promising as improvements over standard automated perimetry; however, there is still no agreed upon method for determination of glaucomatous visual field progression.
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