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The glutathione thiyl radical does not react with nitrogen monoxide.

Dustin Hofstetter1, Thomas Nauser, Willem H Koppenol

  • 1Laboratory for Inorganic Chemistry, Department of Chemistry and Applied Bioscience, ETH Zurich, Wolfgang-Pauli-Strasse 10, CH-8093 Zurich, Switzerland.

Biochemical and Biophysical Research Communications
|June 26, 2007
PubMed
Summary

The reaction between glutathione thiyl radicals and nitrogen monoxide is slower than previously thought. Under physiological conditions, the thiyl radical converts to a carbon-centred form, limiting S-nitrosoglutathione production.

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