Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Single night studies in obstructive sleep apnea.

C Iber1, C O'Brien, J Schluter

  • 1Minnesota Regional Sleep Disorders Center, Minneapolis.

Sleep
|October 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

We can't afford to turn a blind eye to myopia.

QJM : monthly journal of the Association of Physicians·2019
Same author

Improving diagnostic accuracy in clinically ambiguous paediatric appendicitis: a retrospective review of ultrasound and pathology findings with focus on the non-visualised appendix.

The British journal of radiology·2018
Same author

Peripherally Inserted Central Catheters (PICCs) and Potential Cost Savings and Shortened Bed Stays In an Acute Hospital Setting.

Irish medical journal·2018
Same author

<i>In vitro</i> and <i>in vivo</i> Limiting Dilution Assay for Colorectal Cancer.

Bio-protocol·2018
Same author

Children with facial morphoea managing everyday life: a qualitative study.

The British journal of dermatology·2018
Same author

Effect of Intravenous Administration of Cobalt Chloride to Horses on Clinical and Hemodynamic Variables.

Journal of veterinary internal medicine·2017
Same journal

Nighttime light exposure is associated with metabolic dysfunction in schizophrenia: A cross-sectional analysis of the LENS study.

Sleep·2026
Same journal

Sleep Need Outcompetes Preparation: Reframing Sleep Initiation Through Naturalistic Behaviour.

Sleep·2026
Same journal

The Quest for Automated Pediatric Sleep Scoring: Are We There Yet?

Sleep·2026
Same journal

Sex Differences in the Sleep Architecture and Sleep-Disordered Breathing in C57BL/6 J Mice.

Sleep·2026
Same journal

Differential Effects of Prenatal Depression and Anxiety on Infant Sleep: Dual-Pathway Mechanisms Involving the HPA Axis and the Gut-Brain Axis.

Sleep·2026
Same journal

Metabolic Syndrome and Obstructive Sleep Apnea: Two Sides of the Same Coin.

Sleep·2026
See all related articles

Single night studies effectively determine optimal nasal continuous positive airway pressure (CPAP) for most patients with obstructive sleep apnea. This approach conserves resources while ensuring significant improvements in breathing and oxygen levels.

Area of Science:

  • Sleep Medicine
  • Respiratory Physiology

Background:

  • Obstructive sleep apnea (OSA) diagnosis and treatment often involve polysomnography.
  • Determining effective nasal continuous positive airway pressure (CPAP) is crucial for OSA management.

Purpose of the Study:

  • To evaluate the efficacy of single-night studies in establishing effective nasal CPAP pressures.
  • To identify determinants of effective CPAP pressures in patients with OSA.

Main Methods:

  • Analysis of 412 consecutive patients with an apnea index (AI) >= 20 hr-1.
  • Single-night polysomnography with incremental CPAP titration.
  • Assessment of AI, body mass index (BMI), age, and lowest oxygen saturation (SpO2).

Main Results:

Related Experiment Videos

  • Effective CPAP (9 +/- 3 cm H2O) was achieved in 320 patients during single-night studies.
  • A 99% reduction in obstructive events and improved SpO2 to 94 +/- 5% were observed.
  • AI and BMI explained only 18% of the variability in effective CPAP.

    • Conclusions:

    • Single-night studies are sufficient to establish effective CPAP in 78% of OSA patients.
    • Resource conservation is significant compared to multiple-night studies.
    • Effective CPAP pressures are highly variable and necessitate incremental titration.