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[Isolated cough and bronchial asthma].

A Frans1, P Garin, J Van den Eeckhaudt

  • 1Département de Médecine interne, Cliniques universitaires Saint-Luc Belgique.

Revue De Pneumologie Clinique
|January 1, 1991
PubMed
Summary

Persistent non-productive cough may indicate bronchial asthma. A bronchial provocation test is crucial for diagnosis, with symptoms often improving with asthma medications like salbutamol and beclomethasone.

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Area of Science:

  • Pulmonology
  • Allergy and Immunology

Context:

  • Investigated 31 patients with isolated non-productive cough over 18 months.
  • Standard ENT and chest examinations were normal, ruling out other common causes.
  • Patients were not taking angiotensin-converting enzyme inhibitors.

Purpose:

  • To determine if isolated non-productive cough can be the sole manifestation of bronchial asthma.
  • To evaluate the efficacy of bronchial provocation testing in diagnosing cough-variant asthma.
  • To assess the response to asthma medications in patients with cough-variant asthma.

Summary:

  • Acetylcholine inhalation revealed bronchial hyperreactivity in patients with unexplained cough.
  • Three patients exhibited atopy, a common asthma comorbidity.
  • Cough significantly improved with inhaled salbutamol, beclomethasone dipropionate, and sodium cromoglycate for atopic individuals.

Impact:

  • Highlights the importance of considering bronchial asthma in cases of isolated non-productive cough.
  • Emphasizes the diagnostic value of bronchial provocation tests.
  • Demonstrates the therapeutic effectiveness of standard asthma treatments for cough-variant asthma.

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