Related Experiment Video
Updated: Jul 14, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Canine thyroid carcinoma
1Alta Vista Animal Hospital, Ottawa, Ontario, Canada. jliptak@uoguelph.ca
Abstract:
Malignant thyroid carcinomas are relatively common in dogs. The majority of tumors are unilateral and nonfunctional. Before deciding on treatment options, it is important to determine whether the tumor is freely moveable or fixed and invasive into adjacent tissues. Thyroidectomy is recommended for unilateral, mobile thyroid carcinomas. Radiation therapy or radioactive iodine therapy are recommended for dogs with invasive or bilateral thyroid carcinomas. The role of adjunctive chemotherapy is poorly defined, but should be considered in dogs with high-risk tumors, such as large or bilateral thyroid carcinomas. The prognosis is good following surgical treatment of mobile thyroid tumors and irradiation of fixed thyroid carcinomas, with median survival times greater than 3 years.
Related Concept Videos
Hyperthyroidism II: Pathophysiology
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Graves Disease II: Pathophysiology
Hyperthyroidism I: Introduction
Cushing Syndrome II: Pathophysiology
Hypothyroidism II: Pathophysiology

