Related Experiment Video

Updated: Jul 6, 2026

Wild-type Blocking PCR Combined with Direct Sequencing as a Highly Sensitive Method for Detection of Low-Frequency Somatic Mutations
10:41

Wild-type Blocking PCR Combined with Direct Sequencing as a Highly Sensitive Method for Detection of Low-Frequency Somatic Mutations

Published on: March 29, 2017

Selective detection and quantification of oxidized abasic lesions in DNA

Shanta Dhar1, Tetsuya Kodama, Marc M Greenberg

  • 1Department of Chemistry, Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, USA.

Journal of the American Chemical Society
|June 27, 2007
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

Detection of Rare Mutations in CtDNA Using Next Generation Sequencing
11:11

Detection of Rare Mutations in CtDNA Using Next Generation Sequencing

Published on: August 24, 2017

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
12:15

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter

Published on: May 29, 2019

Related Experiment Videos

Last Updated: Jul 6, 2026

Wild-type Blocking PCR Combined with Direct Sequencing as a Highly Sensitive Method for Detection of Low-Frequency Somatic Mutations
10:41

Wild-type Blocking PCR Combined with Direct Sequencing as a Highly Sensitive Method for Detection of Low-Frequency Somatic Mutations

Published on: March 29, 2017

Detection of Rare Mutations in CtDNA Using Next Generation Sequencing
11:11

Detection of Rare Mutations in CtDNA Using Next Generation Sequencing

Published on: August 24, 2017

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
12:15

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter

Published on: May 29, 2019

Related Concept Videos

Base Excision Repair01:54

Base Excision Repair

One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
Base-pairing and DNA Repair02:27

Base-pairing and DNA Repair

Erwin Chargaff’s rules on DNA equivalence paved the way for the discovery of base pairing in DNA. Chargaff’s rules state that in a double-stranded DNA molecule,

Articles linked to this work by shared authors, journal, and citation graph.

A hypofunctional PREX1 variant (p.Y191C) leads to neurodevelopmental abnormalities and epilepsy by attenuating RAC1 signaling.

Scientific reports·2026

Model-guided design of lymphatic drug delivery systems using osmotic pressure, viscosity and lymph node size.

Journal of controlled release : official journal of the Controlled Release Society·2026

Protein-Protein Cross-Linking by a DNA Damage-Derived Histone Modification.

Journal of the American Chemical Society·2026

Mechanistic Studies on DNA Damage via Independent Generation of Purine Reactive Intermediates.

Journal of physical organic chemistry·2026

Synthesis and properties of l-lyxo-thioBsNA-pyrimidine nucleoside: a sulfur-containing analogue of boat-shaped pyranosyl nucleic acid.

RSC chemical biology·2026

DNA-Protein Cross-Link Formation and Cellular Toxicity by Chimeric Bis-Electrophiles.

The Journal of organic chemistry·2026

Small-Molecule Functionalized Needle Transistor Biosensor Enables Direct and Selective Monitoring of SO2 In Vivo.

Analytical chemistry·2026

Direct Visualization of Acute Left Atrial Pressure Elevation During Atrioventricular Nodal Reentrant Tachycardia.

JACC. Case reports·2026

Comparison of automated and manual DNA differential extraction in mock vaginal sexual assault swabs.

Journal of forensic sciences·2026

Cerebral protection in extended arch repair for acute type A aortic dissection.

JTCVS open·2026

Spatially and potential-resolved anti-interference ECL biosensor for simultaneous detection of ochratoxin A and aflatoxin B1.

Talanta·2026

A wash-free and direct SERS platform for non-invasive kidney health monitoring via multiplexed urinary biomarker detection.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us