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Urinary Bladder

Urinary Bladder

The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
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Updated: Jul 14, 2026

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment

Published on: July 28, 2012

[Primary localized bladder amyloidosis].

N Haouas¹, J M Colas

¹Service d'urologie, Centre hospitalier Louis Pasteur, Avenue Léon Jouhaux, 39100 Dole Cedex. noureddinehaouas@yahoo.fr

Revue Medicale Suisse

|June 29, 2007

Summary

Localized pseudo tumoral amyloidosis is a rare urinary tract disease, most often affecting the bladder. Diagnosis relies on histology, distinguishing it from systemic amyloidosis or lymphoma, with conservative treatment preferred unless severe bleeding occurs.

Area of Science:

Nephrology
Urology
Pathology

Context:

Amyloidosis is a group of protein storage diseases.
Localized pseudo tumoral amyloidosis of the urinary tract is rare, with the bladder being the most common site.
Distinguishing this condition from generalized amyloidosis or lymphoproliferative disorders is crucial.

Purpose:

To highlight the diagnostic challenges and treatment considerations for localized pseudo tumoral amyloidosis of the urinary tract.
To emphasize the importance of histological examination in diagnosis.
To outline treatment strategies, prioritizing conservative approaches.

Summary:

This rare urinary tract condition, often presenting as a bladder tumor, requires histological confirmation via cystoscopy samples.

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Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

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Advanced imaging like CT scans and MRI aid in diagnosis but are not definitive.

Investigations must rule out systemic amyloidosis and malignant lymphoproliferation.

Treatment focuses on conservative management, except in cases of massive, recurrent hematuria that threaten prognosis.

Impact:

Improves understanding of a rare urinary tract disease.
Guides diagnostic pathways, emphasizing histological confirmation.
Informs treatment decisions, balancing conservative care with necessary interventions for life-threatening bleeding.