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[Lupus erythematosus and papules. 4 cases]
1Service de Dermatologie Adultes, CHU Timone, Marseille.
Annales De Dermatologie Et De Venereologie
|January 1, 1991
Summary
Papular eruptions in lupus erythematosus (LE) can indicate specific lupoid lesions or mucinosis. These papular manifestations, while uncommon, are significant in diagnosing and understanding the severity of lupus erythematosus.
Area of Science:
- Dermatology
- Rheumatology
- Immunopathology
Background:
- Papular skin eruptions are infrequent in lupus erythematosus (LE), often necessitating differential diagnoses.
- Their presence can signify specific LE-related papular manifestations or mucinosis, either secondary to or associated with LE.
Observation:
- Four cases of papular eruptions in LE patients were analyzed.
- Two cases presented with purely lupoid papules in acute and chronic LE.
- Two cases exhibited papules composed of mucinous deposits, secondary to LE or associated with primary mucinosis.
Findings:
- LE-specific papular manifestations possess a lupoid histological and immunopathological basis.
- In systemic LE, papular eruptions rank fourth in frequency after other common manifestations.
- Papules in LE can suggest mucinosis, which may be secondary to or associated with LE, displaying distinct histological features.
Implications:
- Papular eruptions in LE, particularly when associated with mucinosis, require careful diagnostic consideration.
- Understanding these manifestations aids in assessing the severity and activity of systemic or chronic LE.
- Treatment strategies involving corticosteroids or antimalarial agents show variable efficacy, with LE often being more resistant than mucinosis.