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Updated: Jul 14, 2026

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

GCSDB: an integrated database system for the Georgia Centenarian Study.

Jianliang Dai¹, Adam Davey, Ilene C Siegler

¹The University of Georgia.

|June 29, 2007

Summary

The Georgia Centenarian Study Database (GCSDB) offers insights into factors contributing to extreme longevity. This resource aids in understanding the biological, psychological, and social elements promoting long life.

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Last Updated: Jul 14, 2026

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

Area of Science:

Gerontology
Genetics
Biomedical Informatics

Background:

The Georgia Centenarian Study is a phase III, population-based, multidisciplinary investigation into the factors influencing extreme longevity.
The study enrolled 244 centenarians and near-centenarians (aged 98+), 80 octogenarians, and 400 young controls from Northern Georgia.

Purpose of the Study:

To develop and present the Georgia Centenarian Study Database (GCSDB), an integrated system for managing and analyzing data from centenarian research.
To provide a comprehensive resource for identifying biological, psychological, and social factors, including epistatic interactions, that contribute to exceptional lifespan.

Main Methods:

Development of a web-oriented, integrated database system (GCSDB) housing over 40 relational tables.
Inclusion of diverse participant data: demographics, family history, physical and mental health, cognition, neuropathology, functional capacity, and genetics.
Implementation of data analysis functions for genetic and other data types via the GCSDB website.

Main Results:

The GCSDB integrates extensive data from a cohort of centenarians and controls, covering a wide range of health and genetic parameters.
The database structure supports complex queries to explore relationships between various factors and longevity.
The GCSDB website provides access to data descriptions and analytical tools.

Conclusions:

The GCSDB serves as a valuable, evolving resource for researchers investigating the determinants of human longevity.
Facilitates the identification of key factors and their interactions that enable individuals to reach 100 years and beyond.
Supports future research by providing a robust platform for data exploration and analysis in the field of aging and centenarian studies.