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Surgical management of Crohn's colitis

Christopher R Moir1

  • 1Division of Pediatric Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA. moir.christopher@mayo.edu

Seminars in Pediatric Surgery
|July 3, 2007
PubMed

Insights

Pediatric Crohn

Area of Science:

  • Pediatric gastroenterology and surgery.
  • Inflammatory bowel disease research.

Background:

  • Childhood Crohn's disease is increasing in incidence.
  • Colonic disease is more common in younger children.
  • Colon reconstruction is a more accepted surgical option.

Purpose of the Study:

  • To review unique aspects of pediatric Crohn's colitis.
  • To discuss the complexity of surgical choices for pediatric Crohn's colitis.
  • To highlight recent advances in surgical management.

Main Methods:

  • Review of current literature and clinical practice.
  • Analysis of trends in pediatric Crohn's disease.
  • Discussion of diagnostic and surgical decision-making.

Main Results:

  • Increasing incidence and prevalence of colonic Crohn's disease in children.
  • Growing acceptance of colon reconstruction.
  • Influence of genetic phenotypes on surgical decisions.
  • Emerging role of targeted immunotherapy for durable remissions.
  • Success of less extensive surgeries for intractable colonic disease.

Conclusions:

  • Pediatric Crohn's colitis presents unique challenges for surgeons.
  • Accurate diagnosis and appropriate surgical selection are crucial.
  • Advances in immunotherapy and surgical techniques offer hope for improved outcomes.
  • Less extensive surgery shows promise for children with severe colonic Crohn's disease.

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