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Practical Use of RNA Interference: Oral Delivery of Double-stranded RNA in Liposome Carriers for Cockroaches
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Targeted delivery systems of small interfering RNA by systemic administration

Shigeru Kawakami1, Mitsuru Hashida

  • 1Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan. kawakami@pharm.kyoto-u.ac.jp

Drug Metabolism and Pharmacokinetics
|July 3, 2007
PubMed
Summary

Small interfering RNA (siRNA) holds therapeutic promise, but in vivo delivery faces challenges like degradation and immune responses. This review explores recent advancements in siRNA delivery systems and understanding immune reactions for effective in vivo therapy.

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